Earlier, England suffered collapses at both ends of their innings after home captain Joe Root decided to bat first when winning the toss, despite a green-tinged pitch and overcast conditions offering the promise of assistance to Pakistan's pacemen.
Mohammad Abbas, fresh from starring in Pakistan's five-wicket win over Test debutants Ireland in Dublin last week, led the attack with superb figures of four wickets for 23 runs in just 14 overs.
The recalled Hasan Ali also took a quartet of wickets, with four for 51 in 15.2 overs.
Alastair Cook, playing in a record-equalling 153rd consecutive Test, was the only England batsman to make a fifty, with the left-handed opener scoring 70.
England: Joe Root (c), Jonny Bairstow (wk), Alastair Cook, Mark Stoneman, Dawid Malan, Ben Stokes, Jos Buttler, Chris Woakes, Stuart Broad, Mark Wood, James Anderson, Dominic Bess
Pakistan: Sarfraz Ahmed (c & wk), Azhar Ali, Imam-ul-Haq, Haris Sohail, Asad Shafiq, Babar Azam, Shadab Khan, Faheem Ashraf, Mohammad Amir, Mohammad Abbas, Rahat Ali, Sami Aslam, Fakhar Zaman, Saad Ali, Usman Salahuddin, Hasan Ali
Commentary ( innings)No Records
Alistair CookEngland vs PakistanEngland vs Pakistan 2018hasan aliJoe RootLive Cricket UpdatesPakistan vs England
First Published: May 26, 2018, 7:50 AM IST