Harmanpreet Kaur won the toss and India elected to bat first in in the third and final T20I at Chelmsford.
Katherine Brunt gave England a huge wicket in the very first over of the match getting rid of the dangerous Shafali Verma for a duck.
Smriti Mandhana top-scored for India with a magnificent 70 off just 51 deliveries.
India Women Set England a competitive target of 154 to win the series.
The dismissal of Harmanpreet Kaur by Nat Sciver in the 13th over was a timely wicket for England.
Danni Wyatt gave England a solid start and the hosts had moved to 42 for the loss of one wicket in the powerplay.
Danni Wyatt produced a match-winning undefeated 89 off just 56 deliveries to take England to a thumping 8 wicket victory.
A jubilant Danni Wyatt after England's series win against India at Chelmsford.
The 112 run-stand for the second wicket between Danni Wyatt and Nat Sciver took the match away from India.
England celebrate their T20I series win against India.