PITTSBURGH: Derek Carr threw for 382 yards and two touchdowns, including a 61-yard strike to Henry Ruggs midway through the fourth quarter, and the Las Vegas Raiders beat the Pittsburgh Steelers 26-17 on Sunday.
Carr completed 28 of 37 passes against a Pittsburgh defense that finished the game without a handful of starters, including All-Pro outside linebacker T.J. Watt, who exited in the second quarter with a groin injury.
The Steelers (1-1) lost defensive tackle Tyson Alualu in the first quarter and played the entire game without veteran cornerback Joe Haden and inside linebacker Devin Bush, both of whom were inactive with groin injuries of their own.
Ben Roethlisberger passed for 295 yards for Pittsburgh, including a 25-yard catch-and-run early in the fourth quarter that rookie running back Najee Harris turned into the first touchdown of his career.
The Raiders (2-0) responded immediately. Carr uncorked a rainbow down the middle of the field, giving Ruggs plenty of time to run away from Pittsburghs Minkah Fitzpatrick and Ahkello Witherspoon and into the end zone.
RAMS 27, COLTS 24
INDIANAPOLIS: Matthew Stafford led Los Angeles on two late scoring drives and Matt Gay made a tiebreaking 38-yard field goal with 2:23 to play.
The Rams have won three straight in this series and have taken all five road openers under coach Sean McVay.
Stafford wasnt as proficient as he was in the season-opening victory over Chicago but he did play well even after appearing to hit his right thumb on the helmet of Colts defensive tackle DeForest Buckner in the first half. He finished 19 of 30 for 278 yards, two TD passes and one interception.
Cooper Kupp caught nine passes for 163 yards and two scores for the Rams (2-0).
The Colts are 0-2 for the first time in coach Frank Reichs four-year tenure and now face a daunting three-game road trip.
Indy tied it on a 35-yard field goal with 7:22 left, but quarterback Carson Wentz injured his right ankle on the play before the field goal and did not return. The injury doomed Indys comeback hopes as Jacob Eason was intercepted on his second NFL pass.
BILLS 35, DOLPHINS 0
MIAMI GARDENS, Fla.: Josh Allen threw two touchdown passes, Zach Moss ran for two scores and the Bills knocked out Miami quarterback Tua Tagovailoa early with a rib injury.
Devin Singletary rushed for 82 yards and another touchdown for the Bills (1-1), who have won six consecutive games in the series.
It was the second-worst shutout loss by the Dolphins (1-1) at home, topped only by a 43-0 defeat to New England in 2019.
Tagovailoa lasted only two series, knocked out of the game on a failed fourth-down play near midfield where Buffalos A.J. Epenesa blew past Dolphins right tackle Jesse Davis and was at full speed when he launched into Miamis quarterback. Tagovailoa needed a couple tries just to get to the sideline and was carted to the locker room not long afterward.
Jacoby Brissett took over, completing 24 of 40 passes for 169 yards. Allen completed 17 of 33 passes for 179 yards for Buffalo.
BROWNS 31, TEXANS 21
CLEVELAND: Baker Mayfield came back after hurting his left shoulder to throw a touchdown pass and run for a TD, leading Cleveland to the victory.
Nick Chubb had a 26-yard touchdown run for the Browns (1-1), who bounced back from a Week 1 loss at Kansas City to thrill their first capacity home crowd since 2019.
Mayfield went 10 for 10 after a first-half interception and injuring his non-throwing shoulder while making the tackle on the play and finished 19 of 21 for 213 yards. Chubb had 95 yards on 11 carries.
The Texans (1-1) were tied at halftime and moving the ball with ease before losing quarterback Tyrod Taylor to a hamstring injury.
Taylors injury forced rookie Davis Mills into his first NFL action, and he threw an interception on his second series.
BRONCOS 23, JAGUARS 13
JACKSONVILLE, Fla.: Courtland Sutton had nine catches for 159 yards, and the Broncos handed the Jaguars their 17th consecutive loss.
In Denvers first game without Jerry Jeudy (ankle), Sutton showed he can be Teddy Bridgewaters go-to guy. Sutton’s big day included a shoestring grab in the third quarter that surely rates among his best plays in four seasons.
Sutton had nearly half of Bridgewaters 328 yards passing. Bridgewater completed 26 of 34 passes, with TD tosses to Tim Patrick and Noah Fant.
The Broncos are 2-0 for the seventh time in the last nine years and the first since 2019.
No. 1 overall pick Trevor Lawrence capped an 83-yard drive to open the game with a 25-yard TD pass to Marvin Jones. But Jacksonville (0-2) did little right the rest of the afternoon.
PATRIOTS 25, JETS 6
EAST RUTHERFORD, N.J.: Mac Jones was smart and efficient, Damien Harris and James White had touchdown runs, and the Patriots took advantage of a nightmarish outing by Zach Wilson.
With the spotlight on the Mac vs. Zach matchup of rookie first-round quarterbacks, it was Jones who shined as Wilson was intercepted four times twice by J.C. Jackson.
Jones, the No. 15 overall pick in the draft, went 22 of 30 for 186 yards for the Patriots (1-1) a week after going 29 for 39 for 281 yards and a touchdown in a loss to Miami. Sundays numbers were more than good enough for New England to beat New York for the 11th straight game.
Wilson was 19 of 33 for 210 yards for the Jets (0-2), who have lost 11 straight in September. It got so bad early in the fourth quarter when the No. 2 overall draft pick overthrew a receiver, the crowd at MetLife Stadium began booing the young QB.
49ERS 17, EAGLES 11
PHILADELPHIA: Jimmy Garoppolo threw one touchdown pass and ran in for a score, leading San Francisco to the road win.
Nick Bosa had two sacks and San Franciscos stingy defense shut down Jalen Hurts a week after Philadelphia dominated Atlanta in a 32-6 win.
Hurts completed just 12 of 23 passes for 190 yards. He ran for 82 yards, including a 1-yard TD in the fourth quarter.
The 49ers (2-0) return home after practicing all week at The Greenbrier resort in West Virginia with a pair of road wins on the East Coast to open the season.
The Eagles (1-1) got a reality check in coach Nick Siriannis first home game.
The 49ers went ahead 14-3 in the fourth on Garoppolos sneak from the 1. Robbie Goulds 46-yard field goal made it 17-3.
PANTHERS 26, SAINTS 7
CHARLOTTE, N.C.: Sam Darnold threw for 305 yards and two touchdowns, and Carolina’s defense turned in another strong performance.
Darnold improved to 2-0 as Panthers starter, connecting on TDs to Brandon Zylstra and D.J. Moore as Carolina jumped to a 17-0 lead by outgaining the Saints 274-65 in the first half.
Christian McCaffrey added 137 yards from scrimmage and scored his first touchdown of the season as the Panthers (1-1) defeated the Saints (1-1) for only the second time in the last 10 tries.
Jameis Winston, who threw five TD passes in a 38-3 win over Green Bay in the season opener, was held to 111 yards passing, intercepted twice and sacked four times. Alvin Kamara was limited to 5 yards on eight carries as the Saints struggled with five of the teams offensive coaches out due to COVID-19 protocols. In all, the Saints were missing eight assistant coaches cue to COVID-19.
BEARS 20, BENGALS 17
CHICAGO: Justin Fields played the second half after Andy Dalton exited with a knee injury against his former team, and the rookie quarterback used Chicagos stellar defensive performance to direct the Bears to their first win of the season.
Roquan Smith returned an interception 53 yards for his first career touchdown, one of three straight picks thrown by Joe Burrow.
The Bears were up 20-3 before Burrow threw a 43-yard touchdown to JaMarr Chase. Fields then got intercepted at the Chicago 25 by Logan Wilson, who returned it to the 7. Burrow hit Tee Higgins with a TD on the next play, cutting it to 20-17 with 3:39 remaining. But the Bears (1-1) hung on for their third straight win over Cincinnati (1-1).
Fields, the No. 11 overall draft pick, completed just 6 of 13 passes for 60 yards. He also ran for 31 yards.
Dalton, facing his former team for the second time in as many seasons, threw a touchdown pass to Allen Robinson.
More AP NFL coverage: https://apnews.com/hub/NFL and https://twitter.com/AP_NFL