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Oxford-AstraZeneca Covid Vaccine Can Be Up to 80% Effective With a Delay Between Doses: UK Official

A small shopping basket filled with vials labeled 'COVID-19 - Coronavirus Vaccine' and medical sryinges are placed on an AstraZeneca logo in this illustration taken on November 29, 2020. (REUTERS/Dado Ruvic/Ilustration)

A small shopping basket filled with vials labeled 'COVID-19 - Coronavirus Vaccine' and medical sryinges are placed on an AstraZeneca logo in this illustration taken on November 29, 2020. (REUTERS/Dado Ruvic/Ilustration)

The official said there is insufficient evidence to back a regime involving a half dose of the COVID-19 vaccine.

Oxford and AstraZeneca’s COVID-19 vaccine can be 80% effective when there are three months between shots, an official involved in approving the vaccine in Britain said, but there is insufficient evidence to back a regime involving a half dose.

“Effectiveness was high, up to 80%, when there was a three month interval between first and second doses, which is the reason for our recommendation,” Munir Pirmohamed, Chair of the Commission on Human medicines expert Working Group on COVID-19 vaccines, said on Wednesday.

“We also looked at the half dose regimen, which has been publicised quite widely, but we felt that the results were not borne out by the full analysis,” he said at a news conference where the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) presented its decision.


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