The Indo-Russian pair lost to English third seeds Chris and Gabrielle Adcock 19-21, 15-21 in 37 minutes.
Two other Indians are in the top-25 of men's singles with Kidambi Srikanth at No.5 and H S Prannoy at No.18.
Saina jumped a place to No.4 in women's singles, Srikanth made a leap of six places in the men's singles rankings.
Srikanth grabbed all the headlines by pulling off the biggest upset of his career when he beat Lin Dan to win the men's singles title at the $700,000 tournament.
India's Ponnappa and her Russian partner Ivanov qualified for the main draw of the mixed doubles event at the USD 275,000 French Open Super Series.
Ponnappa-Ivanov lost 18-21, 18-21 in 30 minutes to Hong Kong pair Yun Lung Chan and Ying Suet Tse.
The World Championship bronze medal winning performance has helped Indian shuttler PV Sindhu to re-enter the top-10 in the world.
Jwala and Ashwini were tamed 21-16, 21-8 in the second round of the World Badminton Championships, losing to Qing Tian and Yunlei Zhao.
The Indian badminton squad got off to a poor start as Tarun Kona and Ashwini Ponnappa were ousted from their mixed doubles opener at the World Championships.
Kashyap will be getting a reward of Rs.25 lakh while women's doubles silver medallists Jwala and Ashwini will be awarded Rs.10 lakh each.
The Indian third seeds lost to the second seeded Malaysian duo in straight games 17-21, 21-23 in 41 minutes at the Emirates Arena.
India could not come out with their best show, losing all three doubles matches, including the final crucial women's doubles, to go down to Singapore.
But a Herculean task awaits Saina in the quarter-finals as she takes on world No. 1 Li Xuerui of China.
The World No.21 German pair of Peter Kaesbauer and Isabel Herttrich came from behind after losing the first game 19-21 to win the next two 21-14, 21-19.
The Indian pair moved past Japan's Ayane Kurihara and Naru Shinoya 21-18, 21-16 in 36 minutes in their first match at the Tokyo Metropolitan Gymnasium.
Sindhu beat Hong Kong's Cheung Ngan Yi 21-15, 15-21, 21-18 in an hour to take a 2-0 lead in career meetings.
Saina Nehwal's poor form in international arena continued as she suffered a first round exit in the Singapore Open Super Series while PV Sindhu made her way into the pre-quarterfinals.
Fisher, who won at least eight Superseries titles, praised India's singles shuttlers but said the country needs to change a few things in doubles.
"The results have not been up to the mark recently but I feel we as a team are getting there.Hopefully, we can put up a better show at India Open," Ashwini told.
Women's doubles specialists Jwala Gutta and Ashwini Ponnappa failed to make the main draw of the All England Open Badminton Championships at the National Indoor Arena.
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