The pugilists will aim to match or better the record of four years ago when they managed an impressive tally of nine medals.
Vijender, a former Olympic and World Championships bronze-medallist, outplayed Namibia's Mujandjae Kasuto 3-0 in a lopsided contest to make the last-8 stage.
"No matter what the circumstances, we are prepared for everything," said Olympic medal-winner Vijender Singh.
Shiva Thapa is always a medal favourite for India but a first round exit in London is what has kept him motivated to aim for gold.
Thapa faces World Championship bronze medallist Mykola Butsenko in the 56kg category.
In a major boost for Indian boxing, two young pugilists Shiva Thapa and Sumit Sangwan are headed to Miami after being picked by the American franchise for the World Series of Boxing.
After the afternoon losses of fourth seed Shiva Thapa and sixth seed Manoj Kumar, Vikash Malik and Sumit Sangwan also lost their quarterfinal bouts.
The 19-year-old reigning Asian champion Shiva beat Argentina's Alberto Melian in a split decision of 2-1.
Shiva Thapa and Thokchom Nanao Singh entered the pre-quarters but it was curtains for Vijender Singh, who bowed out after an intense second-round.
Shiva, in the 56kg category, defeated local favourite Obada Alkabeh in the final on a split decision of 2-1 after fighting out a tactically superior bout.
Thapa returned to the country from Amman, Jordan in the wee hours on Wednesday and was all spunk and energy despite being jet-lagged.
A victorious Indian boxing team returned home after a successful Asian Championships where pugilist Shiva Thapa bagged a gold medal.
Thapa, who last year became the youngest Indian to qualify for the Olympics, put up a commanding performance to beat Obada Alkabeh.
Meanwhile, rising star Devendro Singh (49kg) went down fighting to Kazakhstan's Temertas Zhussupov,
L Devendro Singh, Shiva Thapa and Mandeep Jangra continued their fine form to enter the finals of the Asian Boxing Championships in Amman, Jordan.
Bantamweight boxer Shiva Thapa put up an impressive show against Chinese Taipei's Li Lin Yen to book his place in the quarter-finals.
The Indians face a herculean task in the upcoming edition of the Asian Championships.
Due to India's ongoing international suspension, the boxers will compete under the International Boxing Association's (AIBA) flag.
The IABF has been banned, both by AIBA and the Indian sports ministry, due to a faulty electoral process. Most of all, the boxers will suffer.
Sandhu said the setback at the London Olympics has only made the boxers hungrier for success.